3.0
Summary
| Name |  ARHGAP11B
|
| Full Name | Inactive Rho GTPase-activating protein 11B |
| Synonyms | Protein FAM7B1, Rho-type GTPase-activating protein 11B | FAM7B1 |
| Primary ID | Q3KRB8 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex (PubMed:25721503, PubMed:27957544, PubMed:30484771, PubMed:32554627). Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis, thereby playing a key role in neocortex expansion (PubMed:25721503). Promotes the proliferation of basal progenitors by inhibiting the mitochondrial permeability transition pore (mPTP) |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
gtpase-activating protein