Summary

Name TKFC
Full Name Triokinase/FMN cyclase
Synonyms Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing, EC 2.7.1.28, EC 2.7.1.29, Glycerone kinase, Triokinase, Triose kinase, EC 4.6.1.15, FAD-AMP lyase (cyclic FMN forming, FMN cyclase | DAK
Primary ID Q3LXA3
Links - -
Type protein
Relations 2
Function Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response (PubMed:17600090). {ECO:0000250|UniProtKB:F1RKQ4, ECO:0000250|UniProtKB:Q4KLZ6, ECO:0000269|PubMed:16289032, ECO:0000269|PubMed:17600090, ECO:0000269|PubMed:32004446, ECO:0000269|PubMed:4688871}.

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Relations

Regulator Mechanism target score ℹ
+ TKFCdown-regulates quantity img/direct_inhibition.png chemical modification D-glyceraldehyde 0.8
Publications: 1 Organism: Homo Sapiens
+ TKFCdown-regulates quantity img/direct_inhibition.png chemical modification D-glyceraldehyde 3-phosphate(2-) 0.8
Publications: 1 Organism: Homo Sapiens