Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-172536 |
|
|
Homo sapiens |
|
pmid |
sentence |
21383079 |
In this study, we report evidence demonstrating that oatl1, a putative rab guanosine triphosphatase-activating protein (gap), is a novel binding partner of atg8 homologues in mammalian cells. Oatl1 is recruited to isolation membranes and autophagosomes through direct interaction with atg8 homologues and is involved in the fusion between autophagosomes and lysosomes through its gap activity. |
|