Summary

Name FBXO43
Full Name F-box only protein 43
Synonyms Endogenous meiotic inhibitor 2 | EMI2
Primary ID Q4G163
Links - -
Type protein
Relations 1
Function Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (Probable).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation FBXO43 0.381
Publications: 1 Organism: In Vitro