Summary

Name RNFT1
Full Name E3 ubiquitin-protein ligase RNFT1
Synonyms Protein PTD016, RING finger and transmembrane domain-containing protein 1 |
Primary ID Q5M7Z0
Links - -
Type protein
Relations 1
Function E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination RNFT1 0.2
Publications: 1 Organism: Homo Sapiens