Summary

Name WLS
Full Name Protein wntless homolog
Synonyms Integral membrane protein GPR177, Protein evenness interrupted homolog, EVI, Putative NF-kappa-B-activating protein 373 | C1orf139, GPR177
Primary ID Q5T9L3
Links - -
Type protein
Relations 1
Function Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png relocalization WNT3A 0.626
Publications: 1 Organism: Homo Sapiens