Summary

Name OBI1
Full Name ORC ubiquitin ligase 1
Synonyms OBI1, RING finger protein 219 | C13orf7, RNF219
Primary ID Q5W0B1
Links - -
Type protein
Relations 1
Function E3 ubiquitin ligase essential for DNA replication origin activation during S phase (PubMed:31160578). Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase (PubMed:31160578).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination OBI1 0.2
Publications: 1 Organism: Homo Sapiens