Summary

Name IL31
Full Name Interleukin-31
Synonyms IL-31
Primary ID Q6EBC2
Links - -
Type protein
Relations 2
Function Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR (PubMed:15184896). May function in skin immunity (PubMed:15184896). Enhances myeloid progenitor cell survival in vitro (By similarity). Induces RETNLA and serum amyloid A protein expression in macrophages (By similarity).

Viewer

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding OSMR 0.6
Publications: 1 Organism: Homo Sapiens
Tissue: Skin
+ up-regulates img/direct-activation.png binding IL31RA 0.636
Publications: 1 Organism: Homo Sapiens