3.0
Summary
| Name |  RAB12
|
| Full Name | Ras-related protein Rab-12 |
| Synonyms | RAB12_HUMAN | |
| Primary ID | Q6IQ22 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity). |
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guanine nucleotide exchange factor
relocalization