3.0
Summary
| Name |  FAAP20View Modifications |
| Full Name | Fanconi anemia core complex-associated protein 20 |
| Synonyms | FANCA-associated protein of 20 kDa, Fanconi anemia-associated protein of 20 kDa | C1orf86 |
| Primary ID | Q6NZ36 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1. {ECO:0000269|PubMed:22266823, ECO:0000269|PubMed:22343915, ECO:0000269|PubMed:22396592, ECO:0000269|PubMed:22705371}. |
phosphorylation