Summary

Name PSRC1
Full Name Proline/serine-rich coiled-coil protein 1
Synonyms PSRC1_HUMAN | DDA3
Primary ID Q6PGN9
Links - -
Type protein
Relations 1
Function Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation PSRC1 0.235
Publications: 1 Organism: Homo Sapiens