3.0
Summary
| Name |  CRTC3View Modifications |
| Full Name | CREB-regulated transcription coactivator 3 |
| Synonyms | Transducer of regulated cAMP response element-binding protein 3, TORC-3, Transducer of CREB protein 3 | TORC3 |
| Primary ID | Q6UUV7 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). |
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