Summary

Name UNC5D
Full Name Netrin receptor UNC5D
Synonyms Protein unc-5 homolog 4, Protein unc-5 homolog D | KIAA1777, UNC5H4
Primary ID Q6UXZ4
Links - -
Type protein
Relations 1
Function Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity). Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). May play a role in apoptosis in response to DNA damage (PubMed:24691657). It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:24519068). Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity).

Viewer

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding DCC 0.567
Publications: 1 Organism: Homo Sapiens
Tissue: Nervous System