3.0
Summary
| Name |  PACS1View Modifications |
| Full Name | Phosphofurin acidic cluster sorting protein 1 |
| Synonyms | PACS-1 | KIAA1175 |
| Primary ID | Q6VY07 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin-coated membrane pits. Involved in HIV-1 nef-mediated removal of MHC-I from the cell surface to the TGN. |
phosphorylation