3.0
Summary
| Name |  RNF165
|
| Full Name | E3 ubiquitin-protein ligase RNF165 |
| Synonyms | RING finger protein 165 | |
| Primary ID | Q6ZSG1 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | E3 ubiquitin-protein ligase that acts as a regulator of motor axon elongation. Required for efficient motor axon extension in the dorsal forelimb by enhancing the transcriptional responses of the SMAD1/SMAD5/SMAD8 effectors, which are activated downstream of BMP. Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD6, SMAD7, SKI and SNON isoform of SKIL. |
ubiquitination