3.0
Summary
| Name |  MED25
|
| Full Name | Mediator of RNA polymerase II transcription subunit 25 |
| Synonyms | Activator interaction domain-containing protein 1, Activator-recruited cofactor 92 kDa component, ARC92, Mediator complex subunit 25, p78 | ACID1, ARC92, PTOV2 |
| Primary ID | Q71SY5 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for RARA/RXRA-mediated transcription. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MED25 | form complex 
binding
|
Core mediator complex | 0.574 |
| Publications: | 1 | Organism: | Homo Sapiens | |