Summary

Name SSH2
Full Name Protein phosphatase Slingshot homolog 2
Synonyms SSH-like protein 2, SSH-2L, hSSH-2L | KIAA1725, SSH2L
Primary ID Q76I76
Links - -
Type protein
Relations 1
Function Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png dephosphorylation CFL1 0.727
Publications: 1 Organism: Homo Sapiens