4.0
Summary
| Name |  STRADAView Modifications |
| Full Name | STE20-related kinase adapter protein alpha |
| Synonyms | STRAD alpha, STE20-related adapter protein, Serologically defined breast cancer antigen NY-BR-96 | LYK5, STRAD |
| Primary ID | Q7RTN6 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Pathways | AMPK Signaling |
| Function | Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | STK11 | up-regulates activity 
phosphorylation
|
STRADA | 0.939 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| Pathways: | AMPK Signaling | |||
| + | STRADA | up-regulates activity
binding
|
STK11 | 0.939 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | AMPK Signaling | |||