4.0
AMPK Signaling
Pathway ID: SIGNOR-AMPKView in NDEx
Description: Maintaining a balanced level of ATP (the immediate source of cellular energy) is essential for the proper functioning of all living cells. AMP-activated protein kinase (AMPK) is a master regulator of cellular energy homeostasis: AMP-activated protein kinase (AMPK) is activated in response to a fall in ATP (concomitant with a rise in ADP and AMP) level, resulting in the activation of catabolic processes and the inhibition of anabolic processes.
Curated by: Livia Perfetto
Description: Maintaining a balanced level of ATP (the immediate source of cellular energy) is essential for the proper functioning of all living cells. AMP-activated protein kinase (AMPK) is a master regulator of cellular energy homeostasis: AMP-activated protein kinase (AMPK) is activated in response to a fall in ATP (concomitant with a rise in ADP and AMP) level, resulting in the activation of catabolic processes and the inhibition of anabolic processes.
Curated by: Livia Perfetto
26 Seed Entities
Organism: 
|
Name | Primary ID |
|---|---|
| RPS6KA1 | Q15418 |
| ULK1/Atg13/Fip200 | SIGNOR-C100 |
| Gluconeogenesis | SIGNOR-PH35 |
| PPARGC1A | Q9UBK2 |
| STK11 | Q15831 |
| TSC | SIGNOR-C101 |
| SIRT1 | Q96EB6 |
| Autophagy | SIGNOR-PH31 |
| STRADA | Q7RTN6 |
| PDPK1 | O15530 |
| CREB1 | P16220 |
| PFKFB2 | O60825 |
| AMPK | SIGNOR-C15 |
| PIK3CA | P42336 |
| PIP3 | CHEBI:16618 |
| mTORC1 | SIGNOR-C3 |
| INSR | P06213 |
| RHEB | Q15382 |
| Proliferation | SIGNOR-PH4 |
| IRS1 | P35568 |
| FOXO3 | O43524 |
| ERK1/2 | SIGNOR-PF1 |
| INS | P01308 |
| Glycolysis | SIGNOR-PH34 |
| AKT | SIGNOR-PF24 |
| Starvation | SIGNOR-ST4 |