4.0
Summary
| Name |  TICRRView Modifications |
| Full Name | Treslin |
| Synonyms | TopBP1-interacting checkpoint and replication regulator, TopBP1-interacting, replication-stimulating protein | C15orf42 |
| Primary ID | Q7Z2Z1 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation. |
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phosphorylation
phosphorylation