| + |
CNTRL | down-regulates activity 
binding
|
CEP290 |
0.444 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-252149 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18694559 |
CEP290 cooperates with Rab8a to promote ciliogenesis and this function is antagonized by CP110. CP110 in this complex is to keep CEP290 inactive in growing cells until cells are ready to undergo ciliogenesis as they transit into the quiescent state |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HOOK2 | up-regulates 
binding
|
CNTRL |
0.365 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-150956 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17140400 |
Hook2 localizes to the centrosome, binds directly to centriolin/cep110 and contributes to centrosomal function |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CNTRL | down-regulates 
|
Cilium_assembly |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-252150 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18694559 |
CEP290 cooperates with Rab8a to promote ciliogenesis and this function is antagonized by CP110. CP110 in this complex is to keep CEP290 inactive in growing cells until cells are ready to undergo ciliogenesis as they transit into the quiescent state |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
CNTRL
- 
- 