Relation Results

Summary

Name TAF8
Full Name Transcription initiation factor TFIID subunit 8
Synonyms Protein taube nuss, TBP-associated factor 43 kDa, TBP-associated factor 8, Transcription initiation factor TFIID 43 kDa subunit, TAFII-43, TAFII43, hTAFII43 | TAFII43, TBN
Primary ID Q7Z7C8
Links - -
Type protein
Relations 2
Function Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and ...
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Type: Score: Layout: SPV 
0.5420.87TAF8SAGA complexTFIID

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Relations
Regulator
Mechanism
target
score ℹ
+ TAF8form complex img/form-complex.png binding SAGA complex 0.542
Identifier Residue Sequence Organism Cell Line
SIGNOR-269573 Homo sapiens
pmid sentence
Here we present the cryogenic-electron microscopy (cryo-EM) structure of human SAGA (hSAGA)|Human SAGA is a 20-subunit, 1.4-MDa complex with five functional modules (Fig. ​(Fig.1a):1a): a scaffolding core that includes TBP-associated factors (TAFs); a TRRAP (Transformation/Transcription domain Associated Protein) containing a phosphoinositide-3-kinase (PI3K)-related pseudoprotein kinase (ΨPIKK); a histone acetyltransferase (HAT); a deubiquitinase (DUB) and a metazoan-specific splicing (SPL) module
Publications: 1 Organism: Homo Sapiens
+ TAF8form complex img/form-complex.png binding TFIID 0.87
Identifier Residue Sequence Organism Cell Line
SIGNOR-263927 Homo sapiens
pmid sentence
The general transcription factor IID (TFIID) plays a central role in the initiation of RNA polymerase II (Pol II)-dependent transcription by nucleating pre-initiation complex (PIC) assembly at the core promoter. TFIID comprises the TATA-binding protein (TBP) and 13 TBP-associated factors (TAF1-13), which specifically interact with a variety of core promoter DNA sequences.
Publications: 1 Organism: Homo Sapiens
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