Summary

Name MAGI2
Full Name Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Synonyms Atrophin-1-interacting protein 1, AIP-1, Atrophin-1-interacting protein A, Membrane-associated guanylate kinase inverted 2, MAGI-2 | ACVRINP1, AIP1, KIAA0705
Primary ID Q86UL8
Links - -
Type protein
Relations 2
Function Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding DGC 0.26
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ up-regulates activity img/direct-activation.png binding MAGI2 0.417
Publications: 1 Organism: Homo Sapiens
Tissue: Brain