| + |
DHFR2 | down-regulates quantity 
chemical modification
|
dihydrofolate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268260 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21876184 |
Human dihydrofolate reductase (DHFR) was previously thought to be the only enzyme capable of the reduction of dihydrofolate to tetrahydrofolate; an essential reaction necessary to ensure a continuous supply of biologically active folate. |We demonstrate that the DHFRP4, or dihydrofolate reductase-like 1 (DHFRL1), gene is expressed and shares some commonalities with DHFR. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
DHFR2 | up-regulates quantity 
chemical modification
|
(6S)-5,6,7,8-tetrahydrofolate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268261 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21876184 |
Human dihydrofolate reductase (DHFR) was previously thought to be the only enzyme capable of the reduction of dihydrofolate to tetrahydrofolate; an essential reaction necessary to ensure a continuous supply of biologically active folate. |We demonstrate that the DHFRP4, or dihydrofolate reductase-like 1 (DHFRL1), gene is expressed and shares some commonalities with DHFR. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
DHFR2
- 
- 