3.0
Summary
| Name |  CERS3
|
| Full Name | Ceramide synthase 3 |
| Synonyms | CerS3, Dihydroceramide synthase 3, LAG1 longevity assurance homolog 3 | LASS3 |
| Primary ID | Q8IU89 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very-long (C22:0-C24:0) and ultra long chain (more than C26:0) as acyl donor (PubMed:17977534, PubMed:22038835, PubMed:26887952). It is crucial for the synthesis of ultra long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal differentiation (PubMed:23754960). |
chemical modification