Relation Results

Summary

Name NAV2
Full Name Neuron navigator 2
Synonyms Helicase APC down-regulated 1, Pore membrane and/or filament-interacting-like protein 2, Retinoic acid inducible in neuroblastoma 1, Steerin-2, Unc-53 homolog 2, unc53H2 | HELAD1, KIAA1419, POMFIL2, RAINB1, STEERIN2
Primary ID Q8IVL1
Links - -
Type protein
Relations 1
Function Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory ...
View More

Viewer

Type: Score: Layout: SPV 
0.2ZMYND8NAV2

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations
Regulator
Mechanism
target
score ℹ
+ ZMYND8up-regulates quantity by expression img/direct-activation.png transcriptional regulation NAV2 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-266209 Homo sapiens HeLa Cell
pmid sentence
We also confirmed transcriptional coactivator functions of ZMYND8 in ERα-driven reporter assays and on endogenous E2-dependent genes (Figure 5F,G). siRNA knockdown of ZMYND8 showed markedly decreased transcription at the presumptive ERα/Z3 target genes ADORA1 and NAV2, while the classical ERα targets pS2/TFF1 and GREB1 appear to be less affected (Figure 5G), suggesting likely gene-specificity of ZMYND8. 
Publications: 1 Organism: Homo Sapiens
a simple tooltip