Summary

Name PHC2
Full Name Polyhomeotic-like protein 2
Synonyms hPH2, Early development regulatory protein 2 | EDR2, PH2
Primary ID Q8IXK0
Links - -
Type protein
Relations 1
Function Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

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Relations

Regulator Mechanism target score ℹ
+ PHC2form complex img/form-complex.png binding Polycomb repressive complex 1 0.778
Publications: 1 Organism: Homo Sapiens