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Summary
Name
OSCAR
Full Name
Osteoclast-associated immunoglobulin-like receptor
Synonyms
Osteoclast-associated receptor, hOSCAR, Polymeric immunoglobulin receptor 3, PIgR-3, PIgR3, Poly-Ig receptor 3 |
Primary ID
Q8IYS5
Links
-
-
Type
protein
Relations
1
Function
Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. {ECO:0000250}.
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transcriptional regulation
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up-regulates quantity by expression
by organism:
none
by tissue:
none
by cell-line
none
Relations
Regulator
Mechanism
target
score
ℹ
+
SPI1
up-regulates quantity by expression
transcriptional regulation
OSCAR
0.322
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-271689
pmid
sentence
16046394
NFATc1 expression results in the activation of the OSCAR promoter, which was found to be further enhanced by co-expression of PU.1 and microphthalmia-associated transcription factor (MITF).
Publications:
1