Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-274981 |
|
|
Homo sapiens |
A-375 Cell |
pmid |
sentence |
28813410 |
Furthermore, the observations that (i) CMTM6 affects PD-L1 protein stability at late time points after biosynthesis; (ii) CMTM6, CMTM4 and PD-L1 interact, as shown by co-immunoprecipitation; and that (iii) CMTM6 is largely located at the cell surface, collectively suggest a model in which CMTM6 interacts with PD-L1 at the tumour cell surface and thereby protects it from degradation |
|