| + |
RET | up-regulates activity
phosphorylation
|
AFAP1L2 |
0.331 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263192 |
Tyr54 |
SSSSDEEyIYMNKVT |
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 19060924 |
RET/PTC induced robust tyrosine phosphorylation of XB130, which promoted its subsequent association with the p85alpha subunit of phosphatidylinositol 3-kinase (PI 3-kinase). We identified tyrosine 54 of XB130 as the major target of RET/PTC-mediated phosphorylation and a critical binding site for the SH2 domains of p85alpha. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
AFAP1L2 | up-regulates activity
binding
|
PIK3CA |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263193 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 19060924 |
RET/PTC induced robust tyrosine phosphorylation of XB130, which promoted its subsequent association with the p85alpha subunit of phosphatidylinositol 3-kinase (PI 3-kinase). We identified tyrosine 54 of XB130 as the major target of RET/PTC-mediated phosphorylation and a critical binding site for the SH2 domains of p85alpha. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |