3.0
Summary
| Name |  RNF182
|
| Full Name | E3 ubiquitin-protein ligase RNF182 |
| Synonyms | RING finger protein 182, RING-type E3 ubiquitin transferase RNF182 | |
| Primary ID | Q8N6D2 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843). Plays also a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514). |
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polyubiquitination
ubiquitination