Summary

Name DTX3
Full Name Probable E3 ubiquitin-protein ligase DTX3
Synonyms Protein deltex-3, Deltex3, RING finger protein 154, RING-type E3 ubiquitin transferase DTX3 | RNF154
Primary ID Q8N9I9
Links - -
Type protein
Relations 1
Function Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Viewer

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination DTX3 0.2
Publications: 1 Organism: Homo Sapiens