| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270845 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25016522 |
Here, we have systematically investigated the involvement of the catalytic subunit of the human INO80 complex during unchallenged replication and under replication stress by following the effects of its depletion on cell survival, S-phase checkpoint activation, the fate of individual replication forks, and the consequences of fork collapse. We report that INO80 was specifically needed for efficient replication elongation, while it was not required for initiation of replication. |
|
3.0
INO80E
- 
- 
binding