Summary

Name RNF149
Full Name E3 ubiquitin-protein ligase RNF149
Synonyms DNA polymerase-transactivated protein 2, RING finger protein 149, RING-type E3 ubiquitin transferase RNF149 | DNAPTP2
Primary ID Q8NC42
Links - -
Type protein
Relations 2
Function E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination BRAF 0.343
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png ubiquitination RNF149 0.2
Publications: 1 Organism: Homo Sapiens