+ |
ITCH | down-regulates quantity
ubiquitination
|
GLIS3 |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-278653 |
|
|
Homo sapiens |
|
pmid |
sentence |
26147758 |
Itch promotes proteolytic degradation of Glis3.|Since Itch interacts with and ubiquitinates Glis3, it was of interest to determine which regions were necessary for Itch directed degradation of Glis3. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
SUFU | down-regulates
binding
|
GLIS3 |
0.387 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-173573 |
|
|
Homo sapiens |
|
pmid |
sentence |
21543335 |
These data indicate that the inhibition of glis3-mediated transactivation by sufu appears to rely on the interaction with glis3 through the ygh motif and is not related to an effect on the general transcriptional machinery |
|
Publications: |
1 |
Organism: |
Homo Sapiens |