4.0
Summary
| Name |  ACVR1C
|
| Full Name | Activin receptor type-1C |
| Synonyms | Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7 | ALK7 |
| Primary ID | Q8NER5 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Inhibitors | SB 505124 |
| Function | Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. |
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