| Name
|
 LILRB4
|
| Full Name |
Leukocyte immunoglobulin-like receptor subfamily B member 4 |
| Synonyms |
CD85 antigen-like family member K, Immunoglobulin-like transcript 3, ILT-3, Leukocyte immunoglobulin-like receptor 5, LIR-5, Monocyte inhibitory receptor HM18 | ILT3, LIR5 |
| Primary ID |
Q8NHJ6 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. |
4.0
