Summary

Name KIF18A
Full Name Kinesin-like protein KIF18A
Synonyms Marrow stromal KIF18A, MS-KIF18A |
Primary ID Q8NI77
Links - -
Type protein
Relations 2
Function Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.

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Relations

Regulator Mechanism target score
+ up-regulates img/indirect-activation.png Plus-end directed sliding movement 0.7
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png ubiquitination KIF18A 0.301
Publications: 1 Organism: In Vitro