Summary

Name GRPEL2
Full Name GrpE protein homolog 2, mitochondrial
Synonyms Mt-GrpE#2 |
Primary ID Q8TAA5
Links - -
Type protein
Relations 1
Function Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding TIM23 complex 0.5
Publications: 1