Summary

Name RNF217
Full Name E3 ubiquitin-protein ligase RNF217
Synonyms IBR domain-containing protein 1, Opposite STL, RING finger protein 217 | C6orf172, IBRDC1, OSTL
Primary ID Q8TC41
Links - -
Type protein
Relations 1
Function E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination RNF217 0.2
Publications: 1 Organism: Homo Sapiens