Name
|
RNF217
|
Full Name |
E3 ubiquitin-protein ligase RNF217 |
Synonyms |
IBR domain-containing protein 1, Opposite STL, RING finger protein 217 | C6orf172, IBRDC1, OSTL |
Primary ID |
Q8TC41 |
Links |
- - |
Type |
protein |
Relations |
1 |
Function |
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis. |