3.0
Summary
| Name |  CERK
|
| Full Name | Ceramide kinase |
| Synonyms | hCERK, Acylsphingosine kinase, Lipid kinase 4, LK4 | KIAA1646 |
| Primary ID | Q8TCT0 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate (PubMed:11956206, PubMed:16269826, PubMed:19168031). Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines (PubMed:11956206, PubMed:16269826, PubMed:19168031). Shows a greater preference for D-erythro isomer of ceramides (PubMed:16269826). Binds phosphoinositides (PubMed:19168031). |
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