4.0
Summary
| Name |  CEP192View Modifications |
| Full Name | Centrosomal protein of 192 kDa |
| Synonyms | Cep192, Cep192/SPD-2 | KIAA1569 |
| Primary ID | Q8TEP8 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Required for mitotic centrosome maturation and bipolar spindle assembly (PubMed:25042804, PubMed:17980596, PubMed:18207742). Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication (PubMed:25042804, PubMed:17980596, PubMed:18207742). Centrosome-specific activating scaffold for AURKA and PLK1 (PubMed:25042804). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PLK1 | up-regulates activity 
phosphorylation
|
CEP192 | 0.606 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CEP192 | up-regulates activity
binding
|
AURKA | 0.795 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | AURKA | up-regulates activity
phosphorylation
|
CEP192 | 0.795 |
| Publications: | 1 | Organism: | Homo Sapiens | |