Summary

Name CEP192
Full Name Centrosomal protein of 192 kDa
Synonyms Cep192, Cep192/SPD-2 | KIAA1569
Primary ID Q8TEP8
Links - -
Type protein
Relations 2
Function Required for mitotic centrosome maturation and bipolar spindle assembly (PubMed:25042804, PubMed:17980596, PubMed:18207742). Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication (PubMed:25042804, PubMed:17980596, PubMed:18207742). Centrosome-specific activating scaffold for AURKA and PLK1 (PubMed:25042804).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation CEP192 0.593
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding AURKA 0.783
Publications: 1 Organism: Homo Sapiens