| Name
|
 UBASH3B
|
| Full Name |
Ubiquitin-associated and SH3 domain-containing protein B |
| Synonyms |
Cbl-interacting protein p70, Suppressor of T-cell receptor signaling 1, STS-1, T-cell ubiquitin ligand 2, TULA-2, Tyrosine-protein phosphatase STS1/TULA2 | KIAA1959, STS1 |
| Primary ID |
Q8TF42 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination. |
3.0
binding