Summary

Name SCARB1
Full Name Scavenger receptor class B member 1
Synonyms SRB1, CD36 and LIMPII analogous 1, CLA-1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, SR-BI | CD36L1, CLA1
Primary ID Q8WTV0
Links - -
Type protein
Relations 1
Function Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding SRC 0.382
Publications: 1 Organism: Mus Musculus