3.0
Summary
| Name |  PPP1R13LView Modifications |
| Full Name | RelA-associated inhibitor |
| Synonyms | Inhibitor of ASPP protein, Protein iASPP, NFkB-interacting protein 1, PPP1R13B-like protein | IASPP, NKIP1, PPP1R13BL, RAI |
| Primary ID | Q8WUF5 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis (PubMed:12524540). |
phosphorylation