Summary

Name AQP3
Full Name Aquaporin-3
Synonyms AQP-3, Aquaglyceroporin-3 |
Primary ID Q92482
Links - -
Type protein
Relations 1
Function Water channel required to promote glycerol permeability and water transport across cell membranes (PubMed:12239222, PubMed:30420639). Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ PPARAup-regulates quantity by expression img/indirect-activation.png transcriptional regulation AQP3 0.302
Publications: 1 Organism: Homo Sapiens