4.0
Summary
| Name |  RGP1
|
| Full Name | RAB6A-GEF complex partner protein 2 |
| Synonyms | Retrograde Golgi transport protein RGP1 homolog | KIAA0258 |
| Primary ID | Q92546 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | RGP1 | form complex 
binding
|
RIC1-RGP1 guanyl-nucleotide exchange factor complex | 0.762 |
| Publications: | 1 | Organism: | Homo Sapiens | |