Summary

Name PIGK
Full Name GPI-anchor transamidase
Synonyms GPI transamidase, GPI8 homolog, hGPI8, Phosphatidylinositol-glycan biosynthesis class K protein, PIG-K | GPI8
Primary ID Q92643
Links - -
Type protein
Relations 1
Function Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

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Relations

Regulator Mechanism target score ℹ
+ PIGSup-regulates activity img/direct-activation.png binding PIGK 0.941
Publications: 1 Organism: Mus Musculus