Summary

Name AKAP1
Full Name A-kinase anchor protein 1, mitochondrial
Synonyms A-kinase anchor protein 149 kDa, AKAP 149, Dual specificity A-kinase-anchoring protein 1, D-AKAP-1, Protein kinase A-anchoring protein 1, PRKA1, Spermatid A-kinase anchor protein 84, S-AKAP84 | AKAP149, PRKA1
Primary ID Q92667
Links - -
Type protein
Relations 1
Function Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane (By similarity). Involved in mitochondrial-mediated antiviral innate immunity (PubMed:31522117). Promotes translocation of NDUFS1 into mitochondria to regulate mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) activity (By similarity).

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination AKAP1 0.526
Publications: 1 Organism: Homo Sapiens