3.0
Summary
| Name |  PHF21A
|
| Full Name | PHD finger protein 21A |
| Synonyms | BHC80a, BRAF35-HDAC complex protein BHC80 | BHC80, KIAA1696 |
| Primary ID | Q96BD5 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation. |
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